Openfiler and the VMXNET3 / Paravirtualized driver setup

Haven't tested it as of yet but:

http://itblog.rogerlund.net/2009/06/openfiler-23-on-vsphere-using-vmxnet3.html

You will have to modify based on your installation but the conary install of the GCC is essential.

Works spot on! 10GigE connection from a virtualized iSCSI storage device!

Update:
Openfiler does NOT support Persistent Reservations (which is required for 2008 R2 failover clustering), Optional idea.  linux-iscsi.org does support Persistent Reservations, so back to the drawing board. http://linux-iscsi.org/index.php/Persistent_Reservations
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